In this study titled, Prevalence of IgG-mediated food intolerance among patients with allergic symptoms, patients with allergic symptoms such as hives, were evaluated. The study that found that many who elicited allergic symptoms, had no evidence of IgE elevations, thought to be responsible for allergies. However, a significant part of the population did have elevated IgG antibodies, demonstrating that those with histaminergic type reactions, can have an IgG component too.
Conclusion: The detection of a variety of food specific IgG antibodies among patients with allergic symptoms indicates a possible link to food intolerance allergy.
Clinical Take Home: To fully diagnose allergic or inflammatory symptoms, measuring multiple antibodies together gives a clinically more meaningful result.
– Dr. Cheryl Burdette, ND.
Shakoor Z, AlFaifi A, AlAmro B, AlTawil LN, AlOhaly RY. Prevalence of IgG-mediated food intolerance among patients with allergic symptoms. Ann Saudi Med. 2016;36(6):386-390. doi:10.5144/0256-4947.2016.386