Precision Dietary SIgA (Saliva)

Measure Mucosal Immune Health with This Critical Test

Precision Dietary SIgA measures salivary levels of secretory IgA (SIgA) antibodies to 88 different foods. Immunoglobulin A is the most abundant antibody isotype in the mucosal immune system, which lines the mouth, gut, lungs, and genitourinary tract.1 SIgA is your patients’ first line of defense at the mucosal surface, where it binds and neutralizes pathogens, allergens, and toxins.2 SIgA food reactions can generate gut-based inflammation, ultimately contributing to systemic inflammation and suppressing the growth of healthy bacteria in the gut. Hidden SIgA food reactions may explain why your patient hasn’t been responding to the usual treatments.

Indications of Imbalanced Secretory IgA

  • Allergies
  • Atopic conditions
  • Celiac disease
  • Depleted microbiome
  • Dysbiosis or intestinal infections
  • Food sensitivities
  • Increased intestinal permeability
  • Inflammation
  • Inflammatory bowel disease
  • Wheezing

Stop Inflammation and Systemic Effects Caused by SIgA Food Sensitivities

This innovative SIgA panel paints a critical picture of early food reactions at the mucosal surface, the first place where the outside world and internal world meet. SIgA is a pivotal point in the immune system, influencing other branches of the immune system such as IgG and IgE antibody responses. By measuring SIgA, the Precision Allergy IgA Test determines an important cause of the increased inflammation that worsens many pathologies and symptoms such as inflammatory bowel disease,3 celiac disease,4 and respiratory problems. Optimize the health of the mouth, lungs, gut, and genitourinary tract by identifying and addressing SIgA food antibodies.

References

1. Li Y, Jin L, Chen T. The Effects of Secretory IgA in the Mucosal Immune System. BioMed research international. 2020;2020:2032057.
2. Berin MC. Mucosal antibodies in the regulation of tolerance and allergy to foods. Seminars in immunopathology. 2012;34(5):633-642.
3. Warner RH, Stevens FM, McCarthy CF. Salivary SIgA and SIgA 1 in coeliac disease, inflammatory bowel disease and controls. Irish journal of medical science. 1999;168(1):33-35.
4. Brandtzaeg P. Do salivary antibodies reliably reflect both mucosal and systemic immunity? Ann N Y Acad Sci. 2007;1098:288-311.