Precision Allergy 88 (Serum)

The Key to Your Patient’s Health

Precision Allergy 88 is one single test combining IgE, IgG, IgG4 and complement (C3d) reactions to 88 of the most common foods found in the diet. Precision Allergy 88 (previously 588 + Dietary Antigen Testing) was the first test on the market to measure and report immune complexes containing C3d. Complement activation is well-defined in the research as not only a cause of inflammation, but one of the strongest causes (see More Info PDF).

A highly comprehensive test of immune reactions, Precision Point Diagnostics’ Precision Allergy 88 panel helps you identify and address food allergies and food sensitivities in patients with chronic illness. Overt IgE-mediated food allergies can lead to hives, anaphylaxis, or digestive issues while delayed food sensitivities (IgG and IgG4) are linked to sinus problems, acne, gas, bloating, fatigue, constipation, autism, irritable bowel syndrome, and even depression.1 Identifying and eliminating food sensitivities can also assist in the healing of intestinal permeability.

Food Sensitivity Symptoms

  • Diarrhea or loose stool
  • Constipation
  • Gas or bloating
  • Heartburn
  • Rashes, eczema, or swelling
  • Joint pain or inflammation
  • Headaches or migraine
  • Congestion or runny nose
  • Sinus infections
  • Acne
  • Autism
  • Irritable bowel syndrome
  • Fatigue or poor sleep
  • Depression
  • Poor immune defenses
  • Malabsorption of vitamins and minerals

The Most Accurate Food Sensitivity Test

Precision Point Diagnostics provides reliable, reproducible semi-quantitative measurement of IgE, total IgG, and IgG4 using an indirect ELISA (enzyme-linked immunosorbent assay). The system is also capable of detecting immune complexes that contain the complement markers C3D or C1q.

Other food sensitivity tests may have a weak scientific basis or they may not give the full picture of food reactions. Some tests use live cell analysis, which is not a scientifically accepted sign of true food sensitivity or allergic reaction. Other antibody assays may measure total IgG antibodies only; they could miss food reactions that activate the inflammatory complement cascade. Still other tests may measure only a specific IgG subclass and miss out on information about IgG1, IgG2, IgG3, and IgG4, which is reported as total IgG in the Precision Allergy 88.

Better Patient Outcomes

Precision Allergy 88 test results can lead to more precise treatment plans and better patient outcomes. Studies show that patients given an elimination diet based on the results of our food allergy and sensitivity testing experienced fewer headaches and less abdominal pain, diarrhea, constipation, and bloating.2 Knowing exactly what foods your patient reacts to can help to avoid unnecessarily restrictive diets and treatment protocols that inadvertently expose your patient to his or her reactive foods.

The Precision Allergy 88 interpretive report includes more restrictive and less restrictive elimination diets as well as analysis of immune reactions by food groups. This customized report not only helps the clinician use at-a-glance results in clinical practice but also better ensures patient compliance (see sample report).

Precision Allergy 88 can spotlight the dietary components interfering with your patients’ healing. It is the missing piece of the puzzle and can lead to the resolution of previously resistant health problems.

References:

1. Karakula-Juchnowicz H, Gałęcka M, Rog J, et al. The Food-Specific Serum IgG Reactivity in Major Depressive Disorder Patients, Irritable Bowel Syndrome Patients and Healthy Controls. Nutrients. 2018;10(5).
2. Clarke DP, Burdette C, Agolli G, Dorval B, Gaston AM, Chesla S. The relevance of using the C3d/immunoglobulin G test in clinical intervention. Alternative therapies in health and medicine. 2015;21(1):16-27.